Current Projects

Project Name
Description
Investigators
Institutions
Monitoring of plasma RNA levels during chemotherapy treatment for metastatic breast cancer- a feasibility study of blood-based indicators of treatment The purpose of this study is aimed at evaluating a non-invasive test for metastatic breast cancer patients by following a novel RNA biomarker within the blood. Dr Annette Lashman & Dr Sheridan Wilson UoA
Multi Ethnic New Zealand Acute Coronary Syndrome Study (MENZACS) The study aims to understand genetic factors and gene-environment interactions that contribute to disease, outcomes and response to therapy in New Zealand’s ethnically diverse population presenting with first time heart attacks. Prof Rob Doughty &  A/Prof Malcolm Legget UoA
The NETwork! Project: a national study of neuroendocrine cancer The NETwork! Project is a New Zealand wide alliance of cancer clinicians and scientists who are working together in a national framework to manage and study neuroendocrine cancers with the aim of improving outcomes for people with NET cancer. Dr Ben Lawrence UoA
Blood biomarkers for detection of disease burden in patients with melanoma (NSC3) In this University of Auckland study, in part funded by the ‘Healthier Lives’ National Science Challenge, the aim is to develop tests for detecting the growth, immune system response, relapse and outcome of treatment of melanoma Prof Cris Print NSC
Profiling of Oncology Patients as part of Clinical Care and Research (PROSPER) The study is aimed to analyse primary and recurrent tumour samples to then provide molecular biomarker information specific to a patient’s cancer. The hope is that this will allow us to better understand the cancer and potentially identify treatment and trial options. Dr Michelle Wilson UoA
Respiratory Health of Pacific Youth: Risk and Resilience Throughout Childhood The purpose of the study is to examine current respiratory health of Pacific youth at the age of 18-19 years. We will see how this compares with earlier life assessments – looking for risks but also protective effects on lung function and the presence or absence of respiratory conditions. Dr El-Shadan Tautolo AUT, MMH and UoA
Generation of Patient Derived Xenografts as Predictive Preclincal Models of Human Cancer The aim of the study is to use PDX models to provide clinically predictive preclinical models for testing the effectiveness of novel anticancer drugs in preventing tumour growth and to guide the therapy of individual cancer patients.  Dr Ben Lawrence  UoA